S1PR3

Sphingosine-1-phosphate receptor 3 also known as S1PR3 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P3.[5]

S1PR3
Identifiers
AliasesS1PR3, EDG-3, EDG3, LPB3, S1P3, sphingosine-1-phosphate receptor 3
External IDsOMIM: 601965 MGI: 1339365 HomoloGene: 3829 GeneCards: S1PR3
Orthologs
SpeciesHumanMouse
Entrez

1903

13610

Ensembl

ENSG00000213694

ENSMUSG00000067586

UniProt

Q99500

Q9Z0U9

RefSeq (mRNA)

NM_005226

NM_010101

RefSeq (protein)

NP_005217

NP_034231

Location (UCSC)Chr 9: 88.99 – 89.01 MbChr 13: 51.56 – 51.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.[5]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000213694 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000067586 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: S1PR3 sphingosine-1-phosphate receptor 3".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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