TAS2R39

TAS2R39
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GFZ
Identifiers
Aliases	TAS2R39, T2R39, T2R57, taste 2 receptor member 39
External IDs	MGI: 2681308 HomoloGene: 52214 GeneCards: TAS2R39
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	143,184,435 bp[1]
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[2]
End	42,118,829 bp[2]
RNA expression pattern
	Top expressed in
	corpus callosum;
	Top expressed in
	embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; bitter taste receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	259285
	353148
	ENSG00000236398
	ENSMUSG00000047102
	P59534
	Q7TQA5
	NM_176881
	NM_181275
	NP_795362
	NP_851792
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000236398 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000047102 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
"Entrez Gene: TAS2R39 taste receptor, type 2, member 39".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

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