Amelometasone

Amelometasone (developmental code name TS-410) is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2]

Amelometasone
Clinical data
Other namesTS-410; 21-O-Methyl-17-O-propionylbetamethasone; Betamethasone 17-propionate 21-methoxide; 9α-Fluoro-11β,17α-dihydroxy-21-methoxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • [(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11-hydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H35FO6
Molar mass462.558 g·mol−1
3D model (JSmol)
SMILES
  • CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)COC
InChI
  • InChI=1S/C26H35FO6/c1-6-22(31)33-26(21(30)14-32-5)15(2)11-19-18-8-7-16-12-17(28)9-10-23(16,3)25(18,27)20(29)13-24(19,26)4/h9-10,12,15,18-20,29H,6-8,11,13-14H2,1-5H3/t15-,18-,19-,20-,23-,24-,25-,26-/m0/s1
  • Key:ZMYGOSBRLPSJNB-SOMXGXJRSA-N

References
  1. Shepard TH, Lemire RJ (2004). Catalog of Teratogenic Agents. JHU Press. pp. 20–. ISBN 978-0-8018-7953-1.
  2. "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). International Nonproprietary Names (INN) Programme. World Health Organization. 2013.



This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.