Cloprednol

Cloprednol is a synthetic glucocorticoid.[1] It has been investigated for use in asthma.[2]

Cloprednol
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • (9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.023.684
Chemical and physical data
FormulaC21H25ClO5
Molar mass392.873 g·mol−1
3D model (JSmol)
SMILES
  • O=C\1\C=C/[C@]4(C(=C/1)C(\Cl)=C/[C@@H]2[C@@H]4[C@@H](O)C[C@@]3([C@@](O)(C(=O)CO)CC[C@@H]23)C)C

References
  1. Ortega E, Rodriguez C, Strand LJ, Bessler S, Segre E (1976). "Metabolic effects of cloprednol-a new systemic corticosteroid". J Clin Pharmacol. 16 (2–3): 122–8. doi:10.1002/j.1552-4604.1976.tb02393.x. PMID 1254734. S2CID 38774591.
  2. Ellis EF, Morris HG, Kiechel F, Pollock JD, Strand LJ (October 1979). "Short-term efficacy and side effects of cloprednol in children with asthma". J Clin Pharmacol. 19 (10): 675–83. doi:10.1002/j.1552-4604.1979.tb01631.x. PMID 512064. S2CID 38757781.


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