Tixocortol pivalate

Tixocortol pivalate is a corticosteroid. It has anti-inflammatory properties similar to hydrocortisone.[1] It is marketed under the brand name Pivalone.[2]

Tixocortol pivalate
Names
Preferred IUPAC name
S-{2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-Dihydroxy-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl} 2,2-dimethylpropanethioate
Identifiers
CAS Number
3D model (JSmol)
ECHA InfoCard 100.054.261
PubChem CID
UNII
SMILES
  • CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CSC(=O)C(C)(C)C)O)C)O
Properties
Chemical formula
 C26H38O5S
Molar mass 462.64
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

It is sometimes used in patch testing in atopic dermatitis.[3]

See also

References
  1. P Larochelle MD, PhD; P Du Souich MD, PhD; E Bolte MD; J Lelorier MD, PhD & R Goyer PhD (1983). "Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application". Clinical Pharmacology and Therapeutics. 33 (3): 343–350. doi:10.1038/clpt.1983.43. PMID 6402333. S2CID 29876079. Retrieved 2011-03-29.
  2. "Tixocortol Pivalate". Drugs.com. Retrieved 2011-03-29.
  3. Nedorost ST, Babineau D (October 2010). "Patch testing in atopic dermatitis". Dermatitis. 21 (5): 251–4. doi:10.2310/6620.2010.10036. PMID 20920410. S2CID 25026888.


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