Procinonide

Procinonide (developmental code RS-2362; also known as fluocinolone acetonide propionate) is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

Procinonide
Clinical data
Other namesRS-2362; Fluocinolone acetonide propionate; Fluocinolone acetonide 21-propionate; 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-propionate; 6α,9α-Difluoro-11β-hydroxy-16α,17α-[isopropylidenebis(oxy)]pregna-1,4-diene-3,20-dione 21-propionate
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-ox oethyl propionate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard100.055.699
Chemical and physical data
FormulaC27H34F2O7
Molar mass508.559 g·mol−1
3D model (JSmol)
SMILES
  • CCC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3C[C@@H](C5=CC(=O)C=C[C@@]54C)F)F)O)C)OC(O2)(C)C
InChI
  • InChI=1S/C27H34F2O7/c1-6-22(33)34-13-20(32)27-21(35-23(2,3)36-27)11-15-16-10-18(28)17-9-14(30)7-8-24(17,4)26(16,29)19(31)12-25(15,27)5/h7-9,15-16,18-19,21,31H,6,10-13H2,1-5H3/t15-,16-,18-,19-,21+,24-,25-,26-,27+/m0/s1
  • Key:UBOIMZIXNXGQOH-RTWVSBIPSA-N

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1021–. ISBN 978-1-4757-2085-3.


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