Halcinonide

Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification.[1] It is used topically (in a 0.05% cream provided as Halog) in the treatment of certain skin conditions.

Halcinonide
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa682272
Routes of
administration		Topical
ATC code
Identifiers
IUPAC name
  • (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.019.490
Chemical and physical data
FormulaC24H32ClFO5
Molar mass454.96 g·mol−1
3D model (JSmol)
SMILES
  • ClCC(=O)[C@]45OC(O[C@@H]5C[C@@H]2[C@@]4(C[C@H](O)[C@]3(F)[C@@]1(/C(=C\C(=O)CC1)CC[C@@H]23)C)C)(C)C
InChI
  • InChI=1S/C24H32ClFO5/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,26)17(28)11-22(16,4)24(19,31-20)18(29)12-25/h9,15-17,19,28H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1 N
  • Key:MUQNGPZZQDCDFT-JNQJZLCISA-N N
 NY (what is this?)  (verify)

References
  1. Pujos E, Flament-Waton MM, Paisse O, Grenier-Loustalot MF (January 2005). "Comparison of the analysis of corticosteroids using different techniques". Anal Bioanal Chem. 381 (1): 244–54. doi:10.1007/s00216-004-2890-9. PMID 15700162.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.