Fluprednidene

Fluprednidene, also known as fluprednylidene, is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3] An acetate ester of fluprednidene, fluprednidene acetate, in contrast, has been marketed.[1][2][3]

Not to be confused with Fluprednidene acetate.
Fluprednidene
Clinical data
Other namesFluprednylidene; 9α-Fluoro-11β,17α,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • (8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.016.901
Chemical and physical data
FormulaC22H27FO5
Molar mass390.451 g·mol−1
3D model (JSmol)
SMILES
  • C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1CC(=C)[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@@]43C)F)O
InChI
  • InChI=1S/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19-,20-,21-,22-/m0/s1
  • Key:YVHXHNGGPURVOS-SBTDHBFYSA-N

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 570–. ISBN 978-1-4757-2085-3.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 463–. ISBN 978-3-88763-075-1.
  3. Challener CA (1 December 2001). Chiral Drugs. Wiley. p. 490. ISBN 978-0-566-08411-9.



This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.