Tixocortol

Tixocortol is a corticosteroid used as an intestinal anti-inflammatory[1] and decongestant.

Tixocortol
Clinical data
Other names(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-mercaptoacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Identifiers
IUPAC name
  • (11β)-11,17-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.128.190
Chemical and physical data
FormulaC21H30O4S
Molar mass378.53 g·mol−1
3D model (JSmol)
SMILES
  • O=C4\C=C2/[C@]([C@H]1[C@@H](O)C[C@@]3([C@@](O)(C(=O)CS)CC[C@H]3[C@@H]1CC2)C)(C)CC4
InChI
  • InChI=1S/C21H30O4S/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-26)20(15,2)10-16(23)18(14)19/h9,14-16,18,23,25-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 Y
  • Key:YWDBSCORAARPPF-VWUMJDOOSA-N Y
 NY (what is this?)  (verify)

See also

References
  1. Larochelle P, Du Souich P, Bolte E, Lelorier J, Goyer R (March 1983). "Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application". Clinical Pharmacology and Therapeutics. 33 (3): 343–50. doi:10.1038/clpt.1983.43. PMID 6402333. S2CID 29876079.
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