Endrisone

Endrisone (INN) (brand name Aldrisone), or endrysone (USAN), is a synthetic, steroidal glucocorticoid which is or has been marketed in Italy by SIFI.[1][2][3] It is used as a topical and ophthalmic anti-inflammatory drug in the treatment of skin and eye conditions, respectively.[1][2]

Endrisone
Clinical data
Trade namesAldrisone
Other namesDelta-medrysone;[1] 6α-Methyl-11β-hydroxypregna-1,4-diene-3,20-dione; 6α-Methyl-11β-hydroxy-Δ1-progesterone
Routes of
administration		Topical, ophthalmic[1][2]
Identifiers
IUPAC name
  • (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard100.047.587
Chemical and physical data
FormulaC22H30O3
Molar mass342.479 g·mol−1
3D model (JSmol)
SMILES
  • C[C@H]1C[C@H]2[C@@H]3CC[C@@H]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)C(=O)C
InChI
  • InChI=1S/C22H30O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h7-8,10,12,15-17,19-20,25H,5-6,9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1
  • Key:VDNZZIYSCXESNI-ILSZZQPISA-N

See also

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 486–. ISBN 978-1-4757-2085-3.
  2. Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 110–. ISBN 978-94-011-4439-1.
  3. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 386–. ISBN 978-3-88763-075-1.
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