Hydrocortamate

Hydrocortamate (brand names Magnacort, Ulcortis) is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties.[1][2] It is used topically to treat inflammation due to corticosteroid-responsive dermatoses.[3]

Hydrocortamate
Clinical data
Trade namesMagnacort, Ulcort
Other names11β,17α-Dihydroxy-3,20-dioxopregn-4-en-21-yl N,N-diethylglycinate
Routes of
administration		Topical
Pharmacokinetic data
ExcretionHepatic
Identifiers
IUPAC name
  • [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,

    16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl]

    2-(diethylamino)acetate
CAS Number
PubChem CID
PubChem SID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.877
Chemical and physical data
FormulaC27H41NO6
Molar mass475.626 g·mol−1
3D model (JSmol)
SMILES
  • [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)COC(=O)CN(CC)CC
InChI
  • InChI=1S/C27H41NO6/c1-5-28(6-2)15-23(32)34-16-22(31)27(33)12-10-20-19-8-

    7-17-13-18(29)9-11-25(17,3)24(19)21(30)14-26(20,27)4/h13,19-21,24,30,

    33H,5-12,14-16H2,1-4H3
  • Key:FWFVLWGEFDIZMJ-UHFFFAOYSA-N

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 317–. ISBN 978-1-4757-2085-3.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 524–. ISBN 978-3-88763-075-1.
  3. DrugBank DB00769


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