Hydrocortisone hemisuccinate

Hydrocortisone hemisuccinate
Clinical data
Other names	Hydrocortisone hydrogen succinate; Hydrocortisone succinate; Cortisol 21-hemisuccinate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-hemisuccinate
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid;
CAS Number	2203-97-6 ; 110-15-6 (succinic acid);
PubChem CID	16623;
DrugBank	DB14545;
ChemSpider	15760;
UNII	IHV1VP592V;
KEGG	D01442;
ChEBI	CHEBI:31677;
ChEMBL	ChEMBL977;
CompTox Dashboard (EPA)	DTXSID40872905 ;
ECHA InfoCard	100.016.921
Chemical and physical data
Formula	C25H34O8
Molar mass	462.539 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)COC(=O)CCC(=O)O)O)C)O;
	InChI InChI=1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1; Key:VWQWXZAWFPZJDA-CGVGKPPMSA-N;

Hydrocortisone hemisuccinate (USAN), also known as hydrocortisone hydrogen succinate (BANM) or simply hydrocortisone succinate and sold under the brand name Solu-Cortel among many others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester which is used for antiinflammatory and antiallergic indications.[1][2][3]

References

Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 317–. ISBN 978-1-4757-2085-3.
Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 526–. ISBN 978-3-88763-075-1.
Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 145–. ISBN 978-94-011-4439-1.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.