Desoxycorticosterone pivalate

Desoxycorticosterone pivalate
Clinical data
Trade namesZycortal, Percorten V, Percorten M, Neocortin Depositum, Neocortodina Depositum, Neodin Depositum
Other namesDOCP; Deoxycorticosterone pivalate; Desoxycortone pivalate; Deoxycortone pivalate; Percoten pivalate; Desoxycorticosterone trimethylacetate; Desoxycorticosterone trimethyl acetate; DCT; DOC-TMA; SC-46312; 21-Hydroxypregn-4-ene-3,20-dione pivalate; 21-(2,2-Dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione
Routes of
administration		Intramuscular injection
Drug classCorticosteroid; Mineralocorticoid
ATC code
Identifiers
IUPAC name
  • [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.011.242
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Chemical and physical data
FormulaC26H38O4
Molar mass414.586 g·mol−1
3D model (JSmol)
SMILES
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)COC(=O)C(C)(C)C)CCC4=CC(=O)CC[C@]34C
InChI
  • InChI=1S/C26H38O4/c1-24(2,3)23(29)30-15-22(28)21-9-8-19-18-7-6-16-14-17(27)10-12-25(16,4)20(18)11-13-26(19,21)5/h14,18-21H,6-13,15H2,1-5H3/t18-,19-,20-,21+,25-,26-/m0/s1
  • Key:VVOIQBFMTVCINR-WWMZEODYSA-N

Deoxycorticosterone pivalate (DOCP), also known as desoxycorticosterone trimethyl acetate (DOC-TMA or DCT) and sold under the brand names Zycortal, Percorten V, and Percorten M, is a mineralocorticoid medication and a mineralocorticoid ester.[1][2][3][4] It is formulated as a microcrystalline aqueous suspension, is administered by intramuscular injection at regular intervals, and has a prolonged duration of action.[5] The medication is the C21 pivalate (trimethylacetate) ester of 11-deoxycorticosterone.[1][2]

See also

References

  1. 1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 665–. ISBN 978-1-4757-2085-3.
  2. 1 2 Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 307–. ISBN 978-3-88763-075-1.
  3. ↑ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 93–. ISBN 978-94-011-4439-1.
  4. ↑ Negwer M, Scharnow HG (4 October 2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 2721. ISBN 978-3-527-30247-5. [...] Deoxycortone trimethylacetate, Desoxycorticosterone pivalate. Neocortin depositum, Neocortodina depositum. Neodin-Depositum, Percorten M, Percorten pivalate U Mineralocorticoid (salt-regulating)
  5. ↑ Hager HH, Kern W, List PH, Roth HJ (29 July 2013). Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Ärzte und Medizinalbeamte: Wirkstoffgruppen II Chemikalien und Drogen (A-AL). Springer-Verlag. pp. 108–109. ISBN 978-3-662-25655-8.



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