TNIP2
TNIP2 (TNFAIP3 interacting protein 2) هوَ بروتين يُشَفر بواسطة جين TNIP2 في الإنسان.[1][2][3]
المراجع
- "Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2"، J Biol Chem، 276 (32): 30216–23، أغسطس 2001، doi:10.1074/jbc.M100048200، PMID 11390377.
- "ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1"، Blood، 102 (13): 4407–9، ديسمبر 2003، doi:10.1182/blood-2003-05-1602، PMID 12933576.
- "Entrez Gene: TNIP2 TNFAIP3 interacting protein 2"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- Heyninck K؛ De Valck D؛ Vanden Berghe W؛ وآخرون (1999)، "The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN"، J. Cell Biol.، 145 (7): 1471–82، doi:10.1083/jcb.145.7.1471، PMC 2133159، PMID 10385526.
- "Functional redundancy of the zinc fingers of A20 for inhibition of NF-kappaB activation and protein-protein interactions"، FEBS Lett.، 498 (1): 93–7، 2001، doi:10.1016/S0014-5793(01)02504-2، PMID 11389905.
- "The promyelocytic leukemia protein represses A20-mediated transcription"، J. Biol. Chem.، 277 (35): 31734–9، 2002، doi:10.1074/jbc.M201648200، PMID 12080044.
- Strausberg RL؛ Feingold EA؛ Grouse LH؛ وآخرون (2003)، "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "An LKB1-interacting protein negatively regulates TNFalpha-induced NF-kappaB activation"، J. Biomed. Sci.، 10 (2): 242–52، 2003، doi:10.1159/000068708، PMID 12595760.
- "The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2"، Circ. Res.، 92 (6): 630–6، 2003، doi:10.1161/01.RES.0000063422.38690.DC، PMID 12609966.
- "The A20-binding protein ABIN-2 exerts unexpected function in mediating transcriptional coactivation"، FEBS Lett.، 543 (1–3): 55–60، 2003، doi:10.1016/S0014-5793(03)00401-0، PMID 12753905.
- Liu WK؛ Yen PF؛ Chien CY؛ وآخرون (2004)، "The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis"، Biochem. J.، 378 (Pt 3): 867–76، doi:10.1042/BJ20031736، PMC 1224013، PMID 14653779.
- Ota T؛ Suzuki Y؛ Nishikawa T؛ وآخرون (2004)، "Complete sequencing and characterization of 21,243 full-length human cDNAs"، Nat. Genet.، 36 (1): 40–5، doi:10.1038/ng1285، PMID 14702039.
- Bouwmeester T؛ Bauch A؛ Ruffner H؛ وآخرون (2004)، "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway"، Nat. Cell Biol.، 6 (2): 97–105، doi:10.1038/ncb1086، PMID 14743216.
- Lang V؛ Symons A؛ Watton SJ؛ وآخرون (2004)، "ABIN-2 Forms a Ternary Complex with TPL-2 and NF-κB1 p105 and Is Essential for TPL-2 Protein Stability"، Mol. Cell. Biol.، 24 (12): 5235–48، doi:10.1128/MCB.24.12.5235-5248.2004، PMC 419892، PMID 15169888.
- "Overexpression of ABIN-2, a negative regulator of NF-kappaB, delays liver regeneration in the ABIN-2 transgenic mice"، Biochem. Biophys. Res. Commun.، 342 (1): 300–9، 2006، doi:10.1016/j.bbrc.2006.01.114، PMID 16480954.
- Greenberg H؛ Ye X؛ Wilson D؛ وآخرون (2006)، "Chronic intermittent hypoxia activates nuclear factor-kappaB in cardiovascular tissues in vivo"، Biochem. Biophys. Res. Commun.، 343 (2): 591–6، doi:10.1016/j.bbrc.2006.03.015، PMID 16554025.
- Liu Y؛ Nakahara T؛ Miyakoshi J؛ وآخرون (2007)، "Nuclear accumulation and activation of nuclear factor kappaB after split-dose irradiation in LS174T cells"، J. Radiat. Res.، 48 (1): 13–20، doi:10.1269/jrr.0615، PMID 17038805.
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي
بوابة الكيمياء الحيوية
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