Methoxpropamine

Methoxpropamine (MXPr, 2-Oxo-3'-methoxy-PCPr) is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist[1] that is closely related to substances such as methoxetamine and PCPr.[2] It has been sold online as a designer drug, first being identified in Denmark in October 2019,[3] and is illegal in Finland.[4]

Methoxpropamine
Legal status
Legal status
Identifiers
  • 2-(3-Methoxyphenyl)-2-(propylamino)cyclohexanone
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC16H23NO2
Molar mass261.365 g·mol−1
3D model (JSmol)
  • COc1cccc(c1)C2(NCCC)CCCCC2=O
  • InChI=1S/C16H23NO2/c1-3-11-17-16(10-5-4-9-15(16)18)13-7-6-8-14(12-13)19-2/h6-8,12,17H,3-5,9-11H2,1-2H3
  • Key:AAVOSBAXDRASAH-UHFFFAOYSA-N

See also

References
  1. Irie T, Yamazaki D, Kikura-Hanajiri R (July 2021). "A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice". Forensic Toxicology. 39 (2): 474–80. doi:10.1007/s11419-021-00571-0. S2CID 232273277.
  2. Goncalves, R.; Castaing, N.; Richeval, C.; Ducint, D.; Titier, K.; Morvan, E.; Grélard, A.; Loquet, A.; Molimard, M. (April 2022). "Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat". Forensic Science International. 333: 111215. doi:10.1016/j.forsciint.2022.111215. ISSN 0379-0738. PMID 35151938. S2CID 246685658.
  3. "EU Early Warning System Situation Report. Situation report 1" (PDF). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). June 2020.
  4. Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista



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