5-MeO-DiBF

5-MeO-DiBF is a psychedelic[1] that has been sold online as a designer drug and was first definitively identified in December 2015 by a forensic laboratory in Slovenia.[2] It is thought to act as an agonist for the 5-HT1A and 5-HT2 family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DiPT, but with the indole nitrogen replaced by oxygen, making 5-MeO-DiBF a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DiPT and with relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.[3][4]

5-MeO-DiBF
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
  • US: Unscheduled/Illegal if is sold for human consumption.
Identifiers
  • N-[2-(5-Methoxy-1-benzofuran-3-yl)ethyl]-N-(propan-2-yl)propan-2-amine
CAS Number
  • none
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H25NO2
Molar mass275.392 g·mol−1
3D model (JSmol)
  • COC1=CC=C(OC=C2CCN(C(C)C)C(C)C)C2=C1
  • InChI=1S/C17H25NO2/c1-12(2)18(13(3)4)9-8-14-11-20-17-7-6-15(19-5)10-16(14)17/h6-7,10-13H,8-9H2,1-5H3
  • Key:NBFMSQBTYHYVKP-UHFFFAOYSA-N

5-MeO-DiBF is not controlled under the 1971 Convention on Psychotropic Substances, so thus it has a legal grey area in many countries, but it's possible consumption could be persecuted under severe analogue acts if sold for sell human consumption.

See also

References
  1. Casale JF, Hays PA. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal. 9 (1): 39–45.
  2. "Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA" (PDF). European Monitoring Center for Drugs and Drug Addiction.
  3. Tomaszewski Z, Johnson MP, Huang X, Nichols DE (May 1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry. 35 (11): 2061–4. doi:10.1021/jm00089a017. PMID 1534585.
  4. McKenna DJ, Repke DB, Lo L, Peroutka SJ (March 1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology. 29 (3): 193–8. doi:10.1016/0028-3908(90)90001-8. PMID 2139186. S2CID 24188017.
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