Fazadinium bromide

Fazadinium bromide
Clinical data
Trade namesFazadon
ATC code
Identifiers
IUPAC name
  • (E)-bis(3-methyl-2-phenylimidazo[3,2-a]
    pyridin-4-ium-1-yl)diazene dibromide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.051.236
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Chemical and physical data
FormulaC28H24Br2N6
Molar mass604.350 g·mol−1
3D model (JSmol)
SMILES
  • Cc1c(n(c2[n+]1cccc2)N=Nn3c4cccc[n+]4c(c3c5ccccc5)C)c6ccccc6.[Br-].[Br-]
InChI
  • InChI=1S/C28H24N6.2BrH/c1-21-27(23-13-5-3-6-14-23)33(25-17-9-11-19-31(21)25)29-30-34-26-18-10-12-20-32(26)22(2)28(34)24-15-7-4-8-16-24;;/h3-20H,1-2H3;2*1H/q+2;;/p-2 ☒N
  • Key:LBOZSXSPRGACHC-UHFFFAOYSA-L ☒N
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Fazadinium bromide is a muscle relaxant which acts as a nicotinic acetylcholine receptor antagonist through neuromuscular blockade.[1]

References

  1. Camu F, D'Hollander A (1978). "Neuromuscular blockade of fazadinium bromide (AH 8165) in renal failure patients". Acta Anaesthesiologica Scandinavica. 22 (3): 221–6. doi:10.1111/aas.1978.22.3.221. PMID 27936.
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