Difebarbamate

Difebarbamate
Clinical data
Routes of
administration		Oral
ATC code
  • None
Identifiers
IUPAC name
  • (5-ethyl-2,4,6-trioxo-5-phenyldihydropyrimidine-1,3(2H,4H)-diyl)bis-3-butoxypropane-1,2-diyl dicarbamate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.036.147
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Chemical and physical data
FormulaC28H42N4O9
Molar mass578.663 g·mol−1
3D model (JSmol)
SMILES
  • O=C1N(C(=O)N(C(=O)C1(c2ccccc2)CC)CC(OC(=O)N)COCCCC)CC(OC(=O)N)COCCCC
InChI
  • InChI=1S/C28H42N4O9/c1-4-7-14-38-18-21(40-25(29)35)16-31-23(33)28(6-3,20-12-10-9-11-13-20)24(34)32(27(31)37)17-22(41-26(30)36)19-39-15-8-5-2/h9-13,21-22H,4-8,14-19H2,1-3H3,(H2,29,35)(H2,30,36)
  • Key:GJJRIOLBUILIGK-UHFFFAOYSA-N

Difebarbamate (INN) is a tranquilizer of the barbiturate and carbamate families which is used in Europe as a component of a combination drug formulation referred to as tetrabamate (Atrium, Sevrium).[1][2][3]

See also

References

  1. ↑ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 333. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.
  2. ↑ World Health Organization (2004). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substance" (PDF).
  3. ↑ Vachta J, Valter K, Siegfried B (1990). "Metabolism of difebarbamate in man". European Journal of Drug Metabolism and Pharmacokinetics. 15 (3): 191–8. doi:10.1007/BF03190203. PMID 2253648. S2CID 2916646.


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