Nitromethaqualone

Nitromethaqualone
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 2-methyl-3-(2-methoxy-4-nitrophenyl)-4(3H)-quinazolinone
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H13N3O4
Molar mass311.29 g·mol−1
3D model (JSmol)
SMILES
  • O=C1C2=CC=CC=C2N=C(N1C3=C(OC)C=C(N(=O)=O)C=C3)C

Nitromethaqualone[1] is an analogue of methaqualone that has similar sedative and hypnotic properties.[2] It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25 mg.

References

  1. US patent 3162634, Klosa J (Berlin, Germany), "2-Methyl-3-(2'-methyl-3'-chlorphenyl)-quinazolone-(4)", issued 1964-12-22
  2. Szirmai A (November 1963). "[Pharmacological and Therapeutic Studies with a New Quinazolone Derivative, Nitromethaqualone]". Therapeutische Umschau. Revue Therapeutique (in German). 20: 542–6. PMID 14101319.
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