Flutemazepam

Flutemazepam
Clinical data
Pregnancy
category
  • X
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
Identifiers
IUPAC name
  • 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.052.612
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Chemical and physical data
FormulaC16H12ClFN2O2
Molar mass318.730 g·mol−1
3D model (JSmol)
SMILES
  • FC1=CC=CC=C1C2=NC(C(N(C)C3=C2C=C(C=C3)Cl)=O)O
InChI
  • InChI=1S/C16H12ClFN2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3 checkY
  • Key:RMFYWNFETXNTIQ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Flutemazepam[1] was developed at a team at Stabilimenti Chimici Farmaceutici Riuniti SpA in the mid 1970s. Is a drug which is a 3-hydroxy benzodiazepine derivative and an analogue of temazepam that has hypnotic, sedative, amnesiac, anxiolytic, anticonvulsant and skeletal muscle relaxant properties. It is most closely related in structure to temazepam and is indicated for the treatment of severe insomnia.[2] Flutemazepam has properties similar to temazepam, and it has been found to be very effective for the treatment of severe states of anxiety, panic attacks, and severe insomnia.[3]

See also

References

  1. ↑ GB 1431282, "Benzodiazepine Compounds for Therapeutical Use", issued 7 April 1976, assigned to Schiapparelli Farma SpA
  2. ↑ "flutemazepam". psychotropics.dk. Retrieved 11 February 2009.
  3. ↑ Morton IK, Hall JM (1999). Concise Dictionary of Pharmacological Agents. Springer. ISBN 978-0-7514-0499-9.
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