Hexethal

Hexethal
Clinical data
Other namesSodium 5-ethyl-5-hexylbarbiturate, Ortal, Hebaral
ATC code
  • none
Legal status
Legal status
Identifiers
IUPAC name
  • sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H19N2NaO3
Molar mass262.285 g·mol−1
3D model (JSmol)
SMILES
  • [Na+].O=C1/N=C(/[O-])NC(=O)C1(CCCCCC)CC
InChI
  • InChI=1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 checkY
  • Key:HXUAXLUDTCGASZ-UHFFFAOYSA-M checkY
  (verify)

Hexethal (Ortal) is a barbiturate derivative invented in the 1940s. It has sedative, anxiolytic, muscle relaxant, and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine. [1]

Hexethal is considered similar in effects to pentobarbital, with a very fast onset of action but short duration of effects.

References

  1. ↑ Butler TC (October 1950). "The rate of penetration of barbituric acid derivatives into the brain". The Journal of Pharmacology and Experimental Therapeutics. 100 (2): 219–26. PMID 14784958.
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