Taniplon

Taniplon
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 3-(5-methoxy-6,7,8,9-tetrahydroimidazo[1,2-a]quinazolin-2-yl)-5-methyl-1,2,4-oxadiazole
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H15N5O2
Molar mass285.307 g·mol−1
3D model (JSmol)
SMILES
  • CC1=NC(C2=CN3C(N=C(OC)C4=C3CCCC4)=N2)=NO1
InChI
  • InChI=1S/C14H15N5O2/c1-8-15-12(18-21-8)10-7-19-11-6-4-3-5-9(11)13(20-2)17-14(19)16-10/h7H,3-6H2,1-2H3 ☒N
  • Key:OYKONKGGKFFMDV-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Taniplon is a nonbenzodiazepine anxiolytic drug from the imidazoquinazoline family of drugs.

Taniplon binds strongly to benzodiazepine sites on the GABAA receptor and has similar anxiolytic effects in animals, but with less sedative or muscle relaxant action.[1]

References

  1. ↑ Tully WR, Gardner CR, Gillespie RJ, Westwood R (July 1991). "2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors". Journal of Medicinal Chemistry. 34 (7): 2060–7. doi:10.1021/jm00111a021. PMID 1648620.
This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.