PDGFA

Platelet derived growth factor subunit A
المعرفات
الأسماء المستعارة	PDGF-1, PDGFA, platelet-derived growth factor alpha chain, Platelet-derived growth factor A chain, platelet-derived growth factor A-chain, platelet-derived growth factor subunit A, platelet-derived growth factor alpha polypeptide, PDGF A-chain, PDGF subunit A
معرفات خارجية
أورثولوج
	n/a
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	ويكي بيانات
اعرض/عدّل إنسان

PDGFA‏ (Platelet derived growth factor subunit A) هوَ بروتين يُشَفر بواسطة جين PDGFA في الإنسان.[1][2][3]

المراجع

Stenman G, Rorsman F, Huebner K, Betsholtz C (سبتمبر 1992)، "The human platelet-derived growth factor alpha chain (PDGFA) gene maps to chromosome 7p22"، Cytogenet Cell Genet، 60 (3–4): 206–7، doi:10.1159/000133337، PMID 1505216.
Matsui T, Heidaran M, Miki T, Popescu N, La Rochelle W, Kraus M, Pierce J, Aaronson S (مارس 1989)، "Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes"، Science، 243 (4892): 800–4، doi:10.1126/science.2536956، PMID 2536956.
"Entrez Gene: PDGFA platelet-derived growth factor alpha polypeptide"، مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

Nath K, Gogi R, Khan AA, Hameed S (1978)، "Vascular hamartoma and vascular tumours of orbit"، Indian journal of ophthalmology، 25 (1): 18–23، PMID 612586.
Ishibashi T, Bottaro DP, Chan A, وآخرون (1993)، "Expression cloning of a human dual-specificity phosphatase"، Proc. Natl. Acad. Sci. U.S.A.، 89 (24): 12170–4، doi:10.1073/pnas.89.24.12170، PMC 50720، PMID 1281549.
Raines EW, Lane TF, Iruela-Arispe ML, وآخرون (1992)، "The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors"، Proc. Natl. Acad. Sci. U.S.A.، 89 (4): 1281–5، doi:10.1073/pnas.89.4.1281، PMC 48433، PMID 1311092.
Andersson M, Ostman A, Bäckström G, وآخرون (1992)، "Assignment of interchain disulfide bonds in platelet-derived growth factor (PDGF) and evidence for agonist activity of monomeric PDGF"، J. Biol. Chem.، 267 (16): 11260–6، PMID 1317862.
Rorsman F, Leveen P, Betsholtz C (1993)، "Platelet-derived growth factor (PDGF) A-chain mRNA heterogeneity generated by the use of alternative promoters and alternative polyadenylation sites"، Growth Factors، 7 (3): 241–51، doi:10.3109/08977199209046928، PMID 1360804.
Wang Z, Lin XH, Qiu QQ, Deuel TF (1992)، "Modulation of transcription of the platelet-derived growth factor A-chain gene by a promoter region sensitive to S1 nuclease"، J. Biol. Chem.، 267 (24): 17022–31، PMID 1512241.
Bonthron D, Collins T, Grzeschik KH, وآخرون (1992)، "Platelet-derived growth factor A chain: confirmation of localization of PDGFA to chromosome 7p22 and description of an unusual minisatellite"، Genomics، 13 (2): 257–63، doi:10.1016/0888-7543(92)90240-S، PMID 1612586.
Takimoto Y, Wang ZY, Kobler K, Deuel TF (1991)، "Promoter region of the human platelet-derived growth factor A-chain gene"، Proc. Natl. Acad. Sci. U.S.A.، 88 (5): 1686–90، doi:10.1073/pnas.88.5.1686، PMC 51089، PMID 1848007.
Fabisiak JP, Evans JN, Absher M, وآخرون (1991)، "Expression of platelet-derived growth factor A-chain (PDGF-A) mRNA in lung tissue and cells. Complex regulation during remodeling"، Chest، 99 (3 Suppl): 52S–54S، doi:10.1378/chest.99.3_Supplement.52S، PMID 1997274.
Mendoza AE, Young R, Orkin SH, Collins T (1990)، "Increased platelet-derived growth factor A-chain expression in human uterine smooth muscle cells during the physiologic hypertrophy of pregnancy"، Proc. Natl. Acad. Sci. U.S.A.، 87 (6): 2177–81، doi:10.1073/pnas.87.6.2177، PMC 53649، PMID 2315311.
Claesson-Welsh L, Eriksson A, Westermark B, Heldin CH (1989)، "cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor"، Proc. Natl. Acad. Sci. U.S.A.، 86 (13): 4917–21، doi:10.1073/pnas.86.13.4917، PMC 297526، PMID 2544881.
Rorsman F, Bywater M, Knott TJ, وآخرون (1988)، "Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins"، Mol. Cell. Biol.، 8 (2): 571–7، PMC 363182، PMID 2832727.
Beckmann MP, Betsholtz C, Heldin CH, وآخرون (1988)، "Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains"، Science، 241 (4871): 1346–9، doi:10.1126/science.2842868، PMID 2842868.
Bonthron DT, Morton CC, Orkin SH, Collins T (1988)، "Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing"، Proc. Natl. Acad. Sci. U.S.A.، 85 (5): 1492–6، doi:10.1073/pnas.85.5.1492، PMC 279797، PMID 3422746.
Tong BD, Auer DE, Jaye M, وآخرون (1987)، "cDNA clones reveal differences between human glial and endothelial cell platelet-derived growth factor A-chains"، Nature، 328 (6131): 619–21، doi:10.1038/328619a0، PMID 3614363.
Collins T, Bonthron DT, Orkin SH (1987)، "Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain"، Nature، 328 (6131): 621–4، doi:10.1038/328621a0، PMID 3614364.
Hoppe J, Schumacher L, Eichner W, Weich HA (1987)، "The long 3'-untranslated regions of the PDGF-A and -B mRNAs are only distantly related"، FEBS Lett.، 223 (2): 243–6، doi:10.1016/0014-5793(87)80297-1، PMID 3666150.
Betsholtz C, Johnsson A, Heldin CH, وآخرون (1986)، "cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines"، Nature، 320 (6064): 695–9، doi:10.1038/320695a0، PMID 3754619.
Takimoto Y, Li WY, Wang ZY, وآخرون (1993)، "Nucleotide sequence of the 5' region of the human platelet-derived growth factor A-chain gene"، Hiroshima J. Med. Sci.، 42 (1): 47–52، PMID 8486521.

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[pmid1505216-1] Stenman G, Rorsman F, Huebner K, Betsholtz C (سبتمبر 1992)، "The human platelet-derived growth factor alpha chain (PDGFA) gene maps to chromosome 7p22"، Cytogenet Cell Genet، 60 (3–4): 206–7، doi:10.1159/000133337، PMID 1505216.

[pmid2536956-2] Matsui T, Heidaran M, Miki T, Popescu N, La Rochelle W, Kraus M, Pierce J, Aaronson S (مارس 1989)، "Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes"، Science، 243 (4892): 800–4، doi:10.1126/science.2536956، PMID 2536956.

[entrez-3] "Entrez Gene: PDGFA platelet-derived growth factor alpha polypeptide"، مؤرشف من الأصل في 05 ديسمبر 2010.