SFRP4
SFRP4 (Secreted frizzled related protein 4) هوَ بروتين يُشَفر بواسطة جين SFRP4 في الإنسان.[1][2]
الوظيفة
المراجع
- "Entrez Gene: SFRP4 secreted frizzled-related protein 4"، مؤرشف من الأصل في 8 مارس 2010.
- "Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy"، Lab Invest، 79 (4): 439–47، مايو 1999، PMID 10211996.
قراءة متعمقة
- "A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors."، Proc. Natl. Acad. Sci. U.S.A.، 94 (7): 2859–63، 1997، doi:10.1073/pnas.94.7.2859، PMC 20287، PMID 9096311.
- "DDC-4, an apoptosis-associated gene, is a secreted frizzled relative."، FEBS Lett.، 417 (3): 385–9، 1998، doi:10.1016/S0014-5793(97)01324-0، PMID 9409757.
- "Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expression."، Cardiovasc. Res.، 45 (3): 720–8، 2000، doi:10.1016/S0008-6363(99)00376-4، PMID 10728394.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent."، J. Clin. Invest.، 112 (5): 785–94، 2003، doi:10.1172/JCI18563، PMC 182208، PMID 12952927.
- "WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer."، J. Pathol.، 201 (2): 204–12، 2003، doi:10.1002/path.1449، PMID 14517837.
- "Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro."، Clin. Cancer Res.، 10 (2): 615–25، 2004، doi:10.1158/1078-0432.CCR-0707-03، PMID 14760084.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."، Genome Res.، 14 (10B): 2121–7، 2004، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
- "Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus."، J. Biochem. Mol. Biol.، 37 (6): 741–8، 2005، doi:10.5483/bmbrep.2004.37.6.741، PMID 15607035.
- "Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells."، Cancer Res.، 65 (3): 743–8، 2005، PMID 15705870.
- "Secreted frizzled-related protein-4 reduces sodium-phosphate co-transporter abundance and activity in proximal tubule cells."، Pflügers Arch.، 451 (4): 579–87، 2006، doi:10.1007/s00424-005-1495-2، PMID 16151791.
- "Expression of sFRP-4 and beta-catenin in human colorectal carcinoma."، Cancer Lett.، 231 (1): 129–37، 2006، doi:10.1016/j.canlet.2005.01.026، PMID 16356838.
- "Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection."، Clin. Cancer Res.، 12 (7 Pt 1): 2109–16، 2006، doi:10.1158/1078-0432.CCR-05-2468، PMID 16609023.
- "Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer."، Prostate، 67 (10): 1081–90، 2007، doi:10.1002/pros.20607، PMID 17476687.
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