Small nucleolar RNA SNORA48

In molecular biology, Small nucleolar RNA SNORA48 is a pseudouridylation guide H/ACA box snoRNA. This snoRNA was cloned in 2004[1] from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U3797 of 28S rRNA.

Small nucleolar RNA SNORA48
Identifiers
SymbolSNORA48
Alt. SymbolssnoACA48
RfamRF00554
Other data
RNA typeGene; snRNA; snoRNA; H/ACA-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000594
PDB structuresPDBe

The pseudouridylation of this residue had been reported in 1997.[2] The H/ACA box snoRNAs ACA48 and U67, and the C/D box snoRNA mgU6-77, share the same host gene (EIF4A1).

References

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