Small nucleolar RNA psi28S-1192
In molecular biology, Small nucleolar RNA psi28S-1192 (also known as snoRNA psi28S-1192) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
| Small nucleolar RNA psi28S-1192 | |
|---|---|
 Predicted secondary structure and sequence conservation of snopsi28S-1192 | |
| Identifiers | |
| Symbol | snopsi28S-1192 |
| Rfam | RF00542 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; HACA-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000594 |
| PDB structures | PDBe |
This Drosophila-specific snoRNA is a member of the H/ACA box class of snoRNA and is predicted to be responsible for guiding the modification of uridine 1192 to pseudouridine in Drosophila 28S rRNA.[1]
References
- Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.
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