Small nucleolar RNA SNORD28

In molecular biology, Small nucleolar RNA SNORD28 (U28) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U28 is encoded within the U22 snoRNA host gene (UHG) in mammals[1] and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.[2]

Small nucleolar RNA SNORD28
Identifiers
SymbolSNORD28
Alt. SymbolsU28
RfamRF00085
Other data
RNA typeGene; snRNA; snoRNA; CD-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

References

  1. Tycowski KT, Shu MD, Steitz JA (February 1996). "A mammalian gene with introns instead of exons generating stable RNA products". Nature. 379 (6564): 464–6. Bibcode:1996Natur.379..464T. doi:10.1038/379464a0. PMID 8559254. S2CID 4319950.
  2. Tycowski KT, Smith CM, Shu MD, Steitz JA (December 1996). "A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus". Proceedings of the National Academy of Sciences of the United States of America. 93 (25): 14480–5. Bibcode:1996PNAS...9314480T. doi:10.1073/pnas.93.25.14480. PMC 26158. PMID 8962077.
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