Small nucleolar RNA SNORD70

In molecular biology, snoRNA SNORD70 (HBII-234) is a non-coding RNA that belongs to the C/D family of snoRNAs.[1] It is the human orthologue of the mouse MBII-234 and is predicted to guide 2'O-ribose methylation of the small 18S rRNA on position A512.[2] It is hosted, together with HBII-95, by the core C/D box snoRNA protein encoding gene NOP5/NOP58.

Small nucleolar RNA SNORD70
Predicted secondary structure and sequence conservation of SNORD70
Identifiers
SymbolSNORD70
Alt. SymbolssnoHBII-234
RfamRF00575
Other data
RNA typeGene; snRNA; snoRNA; C/D-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

References
  1. Lestrade L, Weber MJ (January 2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Database issue): D158-62. CiteSeerX 10.1.1.105.7552. doi:10.1093/nar/gkj002. PMC 1347365. PMID 16381836.
  2. Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–53. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.
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