Small nucleolar RNA SNORD78

In molecular biology, SNORD78 (also known as U78) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593.[1] The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78 (protein non-coding).[2]

Small nucleolar RNA SNORD78
Predicted secondary structure and sequence conservation of SNORD78
Identifiers
SymbolSNORD78
Alt. SymbolssnoU78
RfamRF00592
Other data
RNA typeGene; snRNA; snoRNA; C/D-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

References
  1. Tycowski KT, Aab A, Steitz JA (November 2004). "Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa". Current Biology. 14 (22): 1985–95. doi:10.1016/j.cub.2004.11.003. PMID 15556860.
  2. Lestrade L, Weber MJ (January 2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Database issue): D158-62. CiteSeerX 10.1.1.105.7552. doi:10.1093/nar/gkj002. PMC 1347365. PMID 16381836.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.