Dexbudesonide

Dexbudesonide
Clinical data
Other namesBudesonide 22R-epimer; 11β,21-Dihydroxy-16α(R),17α-(butylidenebis(oxy))pregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.051.947
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Chemical and physical data
FormulaC25H34O6
Molar mass430.541 g·mol−1
3D model (JSmol)
SMILES
  • CCC[C@@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C
InChI
  • InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21+,22+,23-,24-,25+/m0/s1
  • Key:VOVIALXJUBGFJZ-VXKMTNQYSA-N

Dexbudesonide is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3] It is the 22R-epimer of budesonide.[4]

References

  1. ↑ The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF). World Health Organization. 2013.
  2. ↑ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3560. ISBN 978-3-527-30247-5.
  3. ↑ Wouters J, Quéré L (4 November 2011). Pharmaceutical Salts and Co-crystals. Royal Society of Chemistry. pp. 309–. ISBN 978-1-84973-350-2.
  4. ↑ "(22R)-Budesonide". Toronto Research Chemicals.



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