Bamifylline

Bamifylline
Skeletal formula of bamifylline
Space-filling model of the bamifylline molecule
Names
Preferred IUPAC name
8-Benzyl-7-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.116.522
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PubChem CID
UNII
InChI
  • InChI=1S/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3 checkY
    Key: VVUYEFBRTFASAH-UHFFFAOYSA-N checkY
SMILES
  • O=C2N(c1nc(n(c1C(=O)N2C)CCN(CC)CCO)Cc3ccccc3)C
Properties
Chemical formula
 C20H27N5O3
Molar mass 385.46008
Pharmacology
R03DA08 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.[1][2]

See also

References

  1. ↑ Tomai, F; Crea, F; Gaspardone, A; Versaci, F; De Paulis, R; Polisca, P; Chiariello, L; Gioffrè, PA (June 1996). "Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty". European Heart Journal. 17 (6): 846–53. doi:10.1093/oxfordjournals.eurheartj.a014965. PMID 8781823.
  2. ↑ Kofman, J; Grosclaude, M; Ouechni, MM; Perrin-Fayolle, M (1982). "Comparative effects of bamifylline and theophylline on allergenic bronchospasm induced by the provocative inhalation test: double-blind cross-over study". Le Poumon et le Cœur (in French). 38 (3): 197–202. PMID 6752929.
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