Eticlopride

Eticlopride
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H25ClN2O3
Molar mass340.85 g·mol−1
3D model (JSmol)
SMILES
  • CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl
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Eticlopride is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological research.[1][2][3][4]

References

  1. "Eticlopride hydrochloride". Abcam.
  2. Claytor R, Lile JA, Nader MA (March 2006). "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys". Pharmacology, Biochemistry, and Behavior. 83 (3): 456–64. doi:10.1016/j.pbb.2006.03.007. PMID 16631246. S2CID 39482275.
  3. Hemby SE, Smith JE, Dworkin SI (June 1996). "The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats". The Journal of Pharmacology and Experimental Therapeutics. 277 (3): 1247–58. PMID 8667185.
  4. Haile CN, Kosten TA (November 2001). "Differential effects of D1- and D2-like compounds on cocaine self-administration in Lewis and Fischer 344 inbred rats". The Journal of Pharmacology and Experimental Therapeutics. 299 (2): 509–18. PMID 11602661.
  • Eticlopride at the US National Library of Medicine Medical Subject Headings (MeSH)
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