Normethadone

Normethadone (INN, BAN; brand names Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent. Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grams.[1] The salts in use are the hydrobromide (free base conversion ratio 0.785), hydrochloride (0.890), methyliodide (0.675), oxalate (0.766), picrate (0.563), and the 2,6-ditertbutylnapthalindisulphonate (0.480).[2]

Not to be confused with normethandrone.
Normethadone
Clinical data
Trade namesCophylac
ATC code
Legal status
Legal status
  • AU: S9 (Prohibited substance)
  • CA: Schedule I
  • DE: Anlage III (Special prescription form required)
  • US: Schedule I
Identifiers
IUPAC name
  • 6-dimethylamino-4,4-diphenyl-hexan-3-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.730
Chemical and physical data
FormulaC20H25NO
Molar mass295.426 g·mol−1
3D model (JSmol)
SMILES
  • O=C(C(c1ccccc1)(c2ccccc2)CCN(C)C)CC
InChI
  • InChI=1S/C20H25NO/c1-4-19(22)20(15-16-21(2)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14H,4,15-16H2,1-3H3 Y
  • Key:WCJFBSYALHQBSK-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

See also
  • Methade

References
  1. "Quotas - 2014". Diversion Control Division. U.S. Department of Justice, Drug Enforcement Administration.
  2. Nordegren T (2002). "Normethadone". The A-Z encyclopedia of alcohol and drug abuse. Parkland, Fla.: Brown Walker Press. p. 470. ISBN 978-1-58112-404-0.


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