Codoxime
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Other names | Codoxime |
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ECHA InfoCard | 100.027.660 |
Chemical and physical data | |
Formula | C20H24N2O5 |
Molar mass | 372.421 g·mol−1 |
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Codoxime (Codossima) is an opiate analogue that is a derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects[1] and was found to have moderate potential to cause dependence in animal studies.[2]
References
- ↑ US granted 3153042, Jack Fishman, "Morphinone and Codeinone Derivatives", issued 13 October 1964, assigned to Mozes Juda Lowenstein
- ↑ Jasinski DR, Martin WR (1967). "Assessment of the dependence-producing properties of dihydrocodeinone and codoxime". Clinical Pharmacology and Therapeutics. 8 (2): 266–70. doi:10.1002/cpt196782266. PMID 6021586. S2CID 36504901.
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