HOT-2

HOT-2 (2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PiHKAL.[1]

HOT-2
Names
Preferred IUPAC name
2-[4-(Ethylsulfanyl)-2,5-dimethoxyphenyl]-N-hydroxyethan-1-amine
Other names
2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanaminol
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
InChI
  • InChI=1S/C12H19NO3S/c1-4-17-12-8-10(15-2)9(5-6-13-14)7-11(12)16-3/h7-8,13-14H,4-6H2,1-3H3 Y
    Key: XGFJCRNRWOXGQM-UHFFFAOYSA-N Y
  • InChI=1/C12H19NO3S/c1-4-17-12-8-10(15-2)9(5-6-13-14)7-11(12)16-3/h7-8,13-14H,4-6H2,1-3H3
    Key: XGFJCRNRWOXGQM-UHFFFAOYAO
SMILES
  • CCSc1cc(OC)c(cc1OC)CCNO
Properties
Chemical formula
 C12H19NO3S
Molar mass 257.35 g·mol−1
Melting point 122 °C (252 °F; 395 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Chemistry

HOT-2's full chemical name is 2-[4-(2-ethylthio)-2,5-dimethoxyphenyl–N–hydroxyethanamine. It has structural properties similar to 2C-T-2 and to other drugs in the HOT- series, with the most closely related compounds being HOT-7 and HOT-17.

General information

The dosage range of HOT-2 is typically 10-18 mg and its duration is approximately 6–10 hours according to Shulgin.[1] HOT-2 produces visuals and moving, flowing lights. It also causes euphoria and increases blood pressure.

Legality

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.[2]

See also

References
  1. PiHKAL #87 HOT-2
  2. "UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Retrieved 12 March 2014.
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