4C-T-2
2,5-Dimethoxy-4-ethylthio-α-ethylphenethylamine (4C-T-2) is a synthetic drug of the phenethylamine chemical class. It is the α-ethylated analogue of 2C-T-2.
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Formula | C14H23NO2S |
Molar mass | 269.40 g·mol−1 |
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Pharmacology
Binding profile
4C-T-2 has affinity (Ki) for the 5-HT1A (5,339 nM), 5-HT1E (9,879 nM), 5-HT2A (274.1 nM), 5-HT2B (58.1 nM), 5-HT2C (468.6 nM), 5-HT5A (1,587 nM), 5-HT7 (3,829), D3 (1,273 nM), β2-adrenergic (124.9 nM), I1 (946.5 nM), and σ1 (514 nM) receptors.[1] The activity of 4C-T-2 at these sites has not been assayed, with the exception of the 5-HT2A and 5-HT2C receptors where it acts as a partial agonist.[1]
References
- Ray TS (February 2010). "Psychedelics and the human receptorome". PLOS ONE. 5 (2): e9019. Bibcode:2010PLoSO...5.9019R. doi:10.1371/journal.pone.0009019. PMC 2814854. PMID 20126400.
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See also: Receptor/signaling modulators |
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