Propylamphetamine

Propylamphetamine is a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes which acts as a stimulant. It was first developed in the 1970s, mainly for research into the metabolism of,[1] and as a comparison tool to, other amphetamines.[2] A study in rats found propylamphetamine to be 1/4 as potent as amphetamine.[3]

Propylamphetamine
Clinical data
Other namesN-propyl-1-phenyl-propan-2-amine;
N-propylamphetamine
ATC code
  • none
Legal status
Legal status
  • UK: Not controlled
Pharmacokinetic data
MetabolismHepatic
ExcretionRenal
Identifiers
IUPAC name
  • N-(1-methyl-2-phenylethyl)propan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.215.934
Chemical and physical data
FormulaC12H19N
Molar mass177.291 g·mol−1
3D model (JSmol)
SMILES
  • NC(C)Cc1ccccc1CCC
InChI
  • InChI=1S/C12H19N/c1-3-6-11-7-4-5-8-12(11)9-10(2)13/h4-5,7-8,10H,3,6,9,13H2,1-2H3 Y
  • Key:VMVXCJCVBKWYTF-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

See also

References
  1. Nazarali AJ, Baker GB, Coutts RT, Pasutto FM (1983). "Amphetamine in rat brain after intraperitoneal injection of N-alkylated analogues". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 7 (4–6): 813–6. doi:10.1016/0278-5846(83)90073-8. PMID 6686713. S2CID 35531794.
  2. Valtier S, Cody JT (October 1995). "Evaluation of internal standards for the analysis of amphetamine and methamphetamine". Journal of Analytical Toxicology. 19 (6): 375–80. doi:10.1093/jat/19.6.375. PMID 8926730.
  3. Woolverton WL, Shybut G, Johanson CE (December 1980). "Structure-activity relationships among some d-N-alkylated amphetamines". Pharmacology, Biochemistry, and Behavior. 13 (6): 869–76. CiteSeerX 10.1.1.687.9187. doi:10.1016/0091-3057(80)90221-x. PMID 7208552. S2CID 25123820.
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