Secofentanyl
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Formula | C22H30N2O |
Molar mass | 338.495 g·mol−1 |
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Secofentanyl is an opioid derivative which is an analogue of fentanyl where the piperidine ring has been cleaved to form an open-chain structure. It is around 40x less potent than fentanyl itself but still 5-6x the potency of morphine in animal tests.[1][2]
See also
References
- ↑ Ivanović MD, Mićović I, Vučković S, Prostran M, Todorović Z, Ivanović E, Kiricojević V, Đorđević JB, Došen-Mićović L (2004). "The synthesis and pharmacological evaluation of (+/-)-2, 3-seco-fentanyl analogues". Journal of the Serbian Chemical Society. 69 (11): 955–68. doi:10.2298/JSC0411955I.
- ↑ Lipiński PF, Kosson P, Matalińska J, Roszkowski P, Czarnocki Z, Jarończyk M, Misicka A, Dobrowolski JC, Sadlej J (February 2019). "Fentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis". Molecules (Basel, Switzerland). 24 (4). doi:10.3390/molecules24040740. PMC 6412969. PMID 30791394.
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