OR1N1

OR1N1
Identifiers
Aliases	OR1N1, OR1-26, OR1N3, OR9-22, olfactory receptor family 1 subfamily N member 1
External IDs	MGI: 3030185 HomoloGene: 10583 GeneCards: OR1N1
Gene location (Human)
Chr.	Chromosome 9 (human)[1]
End	122,527,296 bp[1]
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)[2]
End	36,752,672 bp[2]
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; endometrium; ; liver; ; urinary system; ; renal cortex; ; myometrium; ; temporal lobe; ; amygdala;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	138883
	258944
	ENSG00000171505
	ENSMUSG00000075383
	Q8NGS0
	Q8VGK1
	NM_012363
	NM_146942
	NP_036495
	NP_667153
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 1N1 is a protein that in humans is encoded by the OR1N1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000171505 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000075383 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
"Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1".

External links

OR1N1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171505 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000075383 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9500546-5] Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.

[entrez-6] "Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1".

OR1N1

See also

References

Further reading

External links