OR4D1

OR4D1
Identifiers
Aliases	OR4D1, OR17-23, OR4D3, OR4D4P, TPCR16, olfactory receptor family 4 subfamily D member 1
External IDs	MGI: 3030298 HomoloGene: 44975 GeneCards: OR4D1
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	58,159,585 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	87,811,793 bp[2]
RNA expression pattern
	Top expressed in
	lymph node; ; blood; ; cecum; ; pharynx; ; appendix; ; spleen; ; thymus;
	Top expressed in
	secondary oocyte; ; hypothalamus; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; transmembrane signaling receptor activity; signal transducer activity; olfactory receptor activity;
Cellular component	membrane; plasma membrane; integral component of membrane;
Biological process	detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26689
	258407
	ENSG00000141194
	ENSMUSG00000060787
	Q15615
	Q5SW48
	NM_012374; NM_001386095
	NM_146412
	NP_036506
	NP_666524
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 4D1 is a protein that in humans is encoded by the OR4D1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000141194 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000060787 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
"Entrez Gene: OR4D1 olfactory receptor, family 4, subfamily D, member 1".

External links

OR4D1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000141194 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060787 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9119360-5] Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.

[entrez-6] "Entrez Gene: OR4D1 olfactory receptor, family 4, subfamily D, member 1".

OR4D1

See also

References

Further reading

External links