OR2L2

OR2L2
Identifiers
Aliases	OR2L2, HSHTPCRH07, HTPCRH07, OR1-48, OR2L12, OR2L4P, olfactory receptor family 2 subfamily L member 2
External IDs	MGI: 3030001 HomoloGene: 78689 GeneCards: OR2L2
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	248,042,305 bp[1]
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)[2]
End	19,341,016 bp[2]
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; ganglionic eminence; ; substantia nigra; ; hippocampus proper; ; testicle; ; putamen; ; hypothalamus; ; Brodmann area 9; ; spleen; ; amygdala;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity; molecular function;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway; biological process;
	Sources:Amigo / QuickGO
Orthologs
	26246
	258937
	ENSG00000203663
	ENSMUSG00000045341
	Q8NH16
	Q8VGJ5
	NM_001004686; NM_001385855
	NM_146935
	NP_001004686
	NP_667146
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2L2 is a protein that in humans is encoded by the OR2L2 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000203663 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000045341 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.
"Entrez Gene: OR2L2 olfactory receptor, family 2, subfamily L, member 2".

External links

OR2L2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000203663 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045341 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1370859-5] Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.

[entrez-6] "Entrez Gene: OR2L2 olfactory receptor, family 2, subfamily L, member 2".

OR2L2

See also

References

Further reading

External links