OR5B12

OR5B12
Identifiers
Aliases	OR5B12, OR11-241, OR5B12P, OR5B16, OST743, olfactory receptor family 5 subfamily B member 12
External IDs	MGI: 3031279 HomoloGene: 133606 GeneCards: OR5B12
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	58,442,236 bp[1]
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)[2]
End	12,862,219 bp[2]
RNA expression pattern
	Top expressed in
	lymph node; ; gallbladder; ; human musculoskeletal system; ; muscle of leg; ; gastrocnemius muscle;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; odorant binding; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	390191
	258694
	ENSG00000172362
	ENSMUSG00000045126
	Q96R08
	Q8VFW9
	NM_001004733
	NM_146699
	NP_001004733
	NP_666910
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 5B12 is a protein that in humans is encoded by the OR5B12 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000172362 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000045126 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (Sep 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
"Entrez Gene: OR5B12 olfactory receptor, family 5, subfamily B, member 12".

External links

OR5B12+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000172362 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045126 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12213199-5] Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (Sep 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.

[entrez-6] "Entrez Gene: OR5B12 olfactory receptor, family 5, subfamily B, member 12".

OR5B12

See also

References

Further reading

External links