OR5K1

OR5K1
Identifiers
Aliases	OR5K1, HSHTPCRX10, HTPCRX10, OR3-8, olfactory receptor family 5 subfamily K member 1
External IDs	MGI: 3030006 HomoloGene: 45084 GeneCards: OR5K1
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	98,472,924 bp[1]
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)[2]
End	58,583,539 bp[2]
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ventricle; ; left ventricle; ; smooth muscle tissue;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; odorant binding; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26339
	259003
	ENSG00000232382
	ENSMUSG00000071510
	Q8NHB7
	E9Q8F6
	NM_001004736
	NM_147001
	NP_001004736
	NP_667212
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 5K1 is a protein that in humans is encoded by the OR5K1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000232382 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000071510 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.
"Entrez Gene: OR5K1 olfactory receptor, family 5, subfamily K, member 1".

External links

OR5K1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000232382 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000071510 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1370859-5] Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.

[entrez-6] "Entrez Gene: OR5K1 olfactory receptor, family 5, subfamily K, member 1".

OR5K1

See also

References

Further reading

External links