OR5L2

OR5L2
Identifiers
Aliases	OR5L2, HSHTPCRX16, HTPCRX16, OR11-153, olfactory receptor family 5 subfamily L member 2
External IDs	MGI: 3030990 HomoloGene: 72031 GeneCards: OR5L2
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	55,828,154 bp[1]
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)[2]
End	87,783,444 bp[2]
RNA expression pattern
	Top expressed in
	amniotic fluid;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; olfactory receptor activity; G protein-coupled receptor activity; odorant binding;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26338
	258814
	ENSG00000205030
	ENSMUSG00000075144
	Q8NGL0
	n/a
	NM_001004739
	NM_146817
	NP_001004739
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 5L2 is a protein that in humans is encoded by the OR5L2 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000205030 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000075144 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.
"Entrez Gene: OR5L2 olfactory receptor, family 5, subfamily L, member 2".

External links

OR5L2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000205030 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000075144 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1370859-5] Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.

[entrez-6] "Entrez Gene: OR5L2 olfactory receptor, family 5, subfamily L, member 2".

OR5L2

See also

References

Further reading

External links