OR51A7

OR51A7
Identifiers
Aliases	OR51A7, OR11-27, olfactory receptor family 51 subfamily A member 7
External IDs	MGI: 3030410 HomoloGene: 45856 GeneCards: OR51A7
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	4,909,462 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	102,624,367 bp[2]
RNA expression pattern
	Top expressed in
	fundus; ; prostate;
	Top expressed in
	adrenal gland; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	119687
	258248
	ENSG00000176895
	ENSMUSG00000073962
	Q8NH64
	n/a
	NM_001004749
	NM_001001805
	NP_001004749
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 51A7 is a protein that in humans is encoded by the OR51A7 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

As of 2015, OR51A7 was an orphan receptor, meaning that no odorants have been identified which bind to it.[6]

References

GRCh38: Ensembl release 89: ENSG00000176895 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000073962 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: OR51A7 olfactory receptor, family 51, subfamily A, member 7".
de March CA, Ryu S, Sicard G, Moon C, Golebiowski J (September 2015). "Structure–odour relationships reviewed in the postgenomic era". Flavour and Fragrance Journal. 30 (5): 342–361. doi:10.1002/ffj.3249.

External links

OR51A7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000176895 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000073962 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR51A7 olfactory receptor, family 51, subfamily A, member 7".

[6] March CA, Ryu S, Sicard G, Moon C, Golebiowski J (September 2015). "Structure–odour relationships reviewed in the postgenomic era". Flavour and Fragrance Journal. 30 (5): 342–361. doi:10.1002/ffj.3249.

OR51A7

Ligands

See also

References

Further reading

External links