OR2AE1

Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.[3]

OR2AE1
Identifiers
Aliases	OR2AE1, OR2AE2, olfactory receptor family 2 subfamily AE member 1
External IDs	HomoloGene: 128272 GeneCards: OR2AE1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 99,876,062 bp[1] End 99,877,033 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right coronary artery skeletal muscle tissue duodenum gastric mucosa muscle of leg triceps surae gastrocnemius muscle islet of Langerhans prefrontal cortex anterior pituitary n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81392 n/a Ensembl ENSG00000244623 n/a UniProt Q8NHA4 n/a RefSeq (mRNA) NM_001005276 n/a RefSeq (protein) NP_001005276 n/a Location (UCSC) Chr 7: 99.88 – 99.88 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]