OR2A5

OR2A5
Identifiers
Aliases	OR2A5, OR2A11P, OR2A26, OR2A8, OR7-138, OR7-141, olfactory receptor family 2 subfamily A member 5
External IDs	MGI: 3030282 HomoloGene: 64846 GeneCards: OR2A5
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	144,058,845 bp[1]
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[2]
End	42,876,019 bp[2]
RNA expression pattern
	Top expressed in
	gastric mucosa; ; rectum; ; muscle tissue; ; skeletal muscle tissue; ; smooth muscle tissue; ; gallbladder; ; fundus; ; thymus; ; islet of Langerhans; ; ganglionic eminence;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; olfactory receptor activity; G protein-coupled receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	393046
	258270
	ENSG00000221836; ENSG00000284896
	ENSMUSG00000043119
	Q96R48
	Q8VES9
	NM_012365
	NM_146273
	NP_036497
	NP_666385
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2A5 is a protein that in humans is encoded by the OR2A5 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

ENSG00000284896 GRCh38: Ensembl release 89: ENSG00000221836, ENSG00000284896 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000043119 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
"Entrez Gene: OR2A5 olfactory receptor, family 2, subfamily A, member 5".

External links

OR2A5+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] ENSG00000284896 GRCh38: Ensembl release 89: ENSG00000221836, ENSG00000284896 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043119 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9500546-5] Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.

[entrez-6] "Entrez Gene: OR2A5 olfactory receptor, family 2, subfamily A, member 5".

OR2A5

See also

References

Further reading

External links