OR2D2

OR2D2
Identifiers
Aliases	OR2D2, OR11-610, OR2D1, hg27, olfactory receptor family 2 subfamily D member 2
External IDs	OMIM: 608494 MGI: 3647188 HomoloGene: 81541 GeneCards: OR2D2
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	6,892,500 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	106,709,576 bp[2]
RNA expression pattern
	Top expressed in
	right uterine tube; ; endocrine system; ; endocrine gland; ; thyroid gland; ; left lobe of thyroid gland;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	120776
	384732
	ENSG00000166368
	ENSMUSG00000062987
	Q9H210
	E9Q725
	NM_003700
	NM_001162940
	NP_003691
	NP_001156412
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2D2 is a protein that in humans is encoded by the OR2D2 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000166368 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000062987 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.
"Entrez Gene: OR2D2 olfactory receptor, family 2, subfamily D, member 2".

External links

OR2D2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166368 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000062987 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9787077-5] Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.

[entrez-6] "Entrez Gene: OR2D2 olfactory receptor, family 2, subfamily D, member 2".

OR2D2

See also

References

Further reading

External links