OR2L13

Olfactory receptor 2L13 is a protein that in humans is encoded by the OR2L13 gene.[5]

OR2L13
Identifiers
AliasesOR2L13, OR2L14, olfactory receptor family 2 subfamily L member 13
External IDsMGI: 3030000 HomoloGene: 88350 GeneCards: OR2L13
Orthologs
SpeciesHumanMouse
Entrez

284521

259071

Ensembl

ENSG00000196071

ENSMUSG00000056822

UniProt

Q8N349

Q8VGX2

RefSeq (mRNA)

NM_001304535
NM_175911
NM_001395936

NM_147068

RefSeq (protein)

NP_001291464
NP_787107

NP_667279

Location (UCSC)Chr 1: 248.1 – 248.1 MbChr 16: 19.3 – 19.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [5] OR2L13 was recently implicated in regulating platelet reactivity and growth of abdominal aortic aneurysms [6]

See also

References
  1. GRCh38: Ensembl release 89: ENSG00000196071 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000056822 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: OR2L13 olfactory receptor, family 2, subfamily L, member 13".
  6. Morrell CN, Mix D, Aggarwal A, Bhandari R, Godwin M, Owens P, et al. (May 2022). "Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms". The Journal of Clinical Investigation. 132 (9). doi:10.1172/JCI152373. PMC 9057618. PMID 35324479.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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