OR2T2

OR2T2
Identifiers
Aliases	OR2T2, OR1-43, OR2T2P, olfactory receptor family 2 subfamily T member 2
External IDs	HomoloGene: 66506 GeneCards: OR2T2
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	248,455,725 bp[1]
RNA expression pattern
	Top expressed in
	kidney; ; renal cortex; ; skin of abdomen; ; left ventricle;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	401992
	n/a
	ENSG00000275754; ENSG00000196240; ENSG00000276821
	n/a
	Q6IF00
	n/a
	NM_001004136
	n/a
	NP_001004136
	n/a
	Wikidata
View/Edit Human

Olfactory receptor 2T2 is a protein that in humans is encoded by the OR2T2 gene.[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

References

ENSG00000196240, ENSG00000276821 GRCh38: Ensembl release 89: ENSG00000275754, ENSG00000196240, ENSG00000276821 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
"Entrez Gene: OR2T2 olfactory receptor, family 2, subfamily T, member 2".

External links

OR2T2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] ENSG00000196240, ENSG00000276821 GRCh38: Ensembl release 89: ENSG00000275754, ENSG00000196240, ENSG00000276821 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14983052-3] Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

[entrez-4] "Entrez Gene: OR2T2 olfactory receptor, family 2, subfamily T, member 2".

OR2T2

See also

References

Further reading

External links